AMERICA’S #1 PRESCRIBED BRANDED ORAL MEDICATION7*

Synthroid has been committed to treating hypothyroidism for over six decades.8

  • It’s America’s #1 prescribed branded oral medication7*
  • Millions of patients manage their hypothyroidism with Synthroid9†

*2015-2018.
†2015.

Synthroid has been committed to treating hypothyroidism for over six decades.8

  • It’s America’s #1 prescribed branded oral medication7*
  • Millions of patients manage their hypothyroidism with Synthroid9†

*2015-2018.
†2015.

Synthroid has been committed to treating hypothyroidism for over six decades.8

  • It’s America’s #1 prescribed branded oral medication7*
  • Millions of patients manage their hypothyroidism with Synthroid9†

*2015-2018.
†2015.

ABBVIE IS COMMITTED TO MANUFACTURING INTEGRITY

In August 2002, the FDA released the Current Good Manufacturing Practices (CGMP) initiative to ensure the quality of drug products. The initiative contains minimum requirements for the methods, facilities, and controls used in manufacturing, processing, and packing of a drug product. These regulations make sure that a product is safe for use, and that it has the ingredients and strength it claims to have.5,6

AbbVie is committed to adhering to the CGMP and believes in the integrity of its manufacturing process. AbbVie is dedicated to ensuring that all Synthroid products are manufactured at the highest standards.

Note that FDA regulations require that all pharmaceutical manufacturers like AbbVie abide by CGMP.

ARE PATIENTS GETTING SYNTHROID AS YOU PRESCRIBED?

37% of patients who think they are on
Synthroid actually are not12*

That’s because substitutions can be made at the pharmacy if the prescription is not properly protected with the Dispense as Written (DAW) state-specific language.

Source: Ten-week prescription survey of 538 pharmacies (average 54 prescriptions per state) totalling 2,526 new and renewal Synthroid prescriptions between May 10 and July, 2017. Rx AnalystSM, DMD.14

The FDA has determined that certain levothyroxine products are interchangeable. The FDA has determined that drugs that are classified as therapeutically equivalent can be substituted with the full expectation that the substituted product will produce the same clinical effect and safety profile as the reference product.15

*Mistaken generic users defined as those who reported taking Synthroid but were not taking a pill with the word “SYNTHROID” embossed on it. From a 2017 national online survey of 501 adults diagnosed with hypothyroidism and currently taking LT4 products.10

PREVENTING NONMEDICAL SUBSTITUTION AT THE PHARMACY13

DAW codes are codes a pharmacy uses when filling your patient’s prescription. DAW-1 indicates that substitution is not allowed, based on the prescriber’s preference, and ensures your patient will receive the treatment you prescribe. It also helps your patient pay the lowest possible price for the product you write if it is billed through insurance.

When prescribing Synthroid, protecting your script can ensure your patients receive Synthroid every time they refill their prescription.

Dispense as Written (DAW); Synthroid refills

Tablets shown not actual size and may not represent exact color.

Synthroid Patient 1

Consider the following when switching from Synthroid

Certain levothyroxine products have been determined to be therapeutically equivalent by the FDA

A levothyroxine product that is not therapeutically equivalent to Synthroid might not have the exact same effect on a patient’s TSH levels as Synthroid11

Switching between nontherapeutically equivalent levothyroxine treatments may lead to:

  • Additional patient visits
  • Additional laboratory tests

All hypothyroidism patients, including those remaining on consistent therapy, should have their TSH tested on a regular basis as recommended by their doctor

Small dose changes in levothyroxine, including Synthroid, can affect TSH levels4

Successful management requires very specific and individualized patient dosing.